Be Cool, Scooby-Doo (Catfish Co.) is another incarnation of the long-running Hanna-Barbera Saturday morning cartoon Scooby-Doo. It is a fan made take on Be Cool, Scooby-Doo, and was created by Catfish Co.
Frank Welker does the voices of Fred and Scooby. Matthew Lillard does Shaggy's voice, Grey DeLisle does Daphne's voice, and Kate Micucci does Velma's voice. In each episode, Scooby and the gang go somewhere and encounter a mystery. The mysteries always have a monster or a ghost as the villain; next the gang splits up and finds clues. At the end, Fred sets a trap. After the monster is caught it turns out to be a person in a costume. The villains always have a motive; some might be smugglers, some might be revenge-seekers, they could be anything. Some old monsters are reused.
The gang goes to an observatory to view a presentation on space, however it seems that a constellation has come to life and is wreaking havoc on an astronomer.
A mouse demon haunts an old graveyard that the gang winds up at. And to make things worse, Scooby and the gang are out of gas and must stay at the creepy hotel near it. But the gang each splits up into groups to investigate the mystery in secret, not knowing the other members are also trying...
Fred's uncle breaks his leg and Fred offers to do his job for a few days, being the security guard of a restaurant. He takes the gang, and they encounter a mystery!
The gang goes to a video game convention, but things get scary when a dinosaur from a video game appears in the real world and begins destroying the convention!
The gang visits the set of Fred's favorite kids's show. While investigating the mystery there Fred hits his head and loses his memory of how to be a leader!
The gang travels to a small island country that seems to be stuck in medieval times. The country's soon-to-be queen is haunted by an Evil Witch who can transform into a dragon.
The gang heads to Venice, Italy for a relaxing vacation. However, a masked monster is haunting the area. With Daphne trying to learn about her Venetian ancestors, Shaggy and Scooby trying to try all the food, Velma trying to stay away from the water, and Fred getting too many ideas from scam artists, will they be able to solve the case in time?
The gang gets a job at a fast food restaurant after needing money during a previous Mystery. Will the gang be able to keep their jobs, however, when a Zombie Cow is running around?
The gang rents a cabin in the woods over the weekend so that Fred can reconnect with his family's history. However, Daphne fears a curse is coming back to haunt her, and begins carving figurines of Fred to protect him. And to make matters worse, a muscular demon that looks suspiciously like Fred is terrorizing the woods.
Chimeras are the newest pet craze and Fred got one of his own, leaving Scooby jealous. However, when some Chimeras begin transforming into monstrous and feral beasts, will the gang be able to get to the root of these problematic pets? And will Daphne be able to pass her summer Home Economics class by taking care of an egg?
When Shaggy and Scooby have a disagreement about their plans to start a muffin bakery, they decide to go their separate ways and begin competing on the streets of San Francisco to outdo the other in friendly muffin selling competition. But it seems they may have more competition when expected, when a mysterious muffin selling ghost takes to the streets!
Daphne, feeling Velma is not adventurous enough, arranges for them to go to Alaska and visit the wilderness. Velma initially objects to the idea, but Daphne persuades her to go. However, they soon uncover a poaching scheme. Velma tries to report it to the local authorities, and meanwhile Daphne gets sick. To complicate matters, a demonic moose begins haunting the area.
When Scooby wakes up to the horrifying realization he is growing a beard, he demands to go to the barber. Yet Daphne sees potential in it and brings the gang to a national beard competition. However, it isn't long before a ghost barber starts terrorizing the contestants! Worse yet, Shaggy begins to suspect Scooby has stolen his beard.
After Daphne's grandmother dies, Daphne brings the gang to her home in Florida. The Blake family is planning to clear it out and is sell it, and Daphne brings the gang there to take a final look. Meanwhile, a demonic roseate spoonbill begins to target them.