Frank Welker does the voices of Fred and Scooby. Matthew Lillard does Shaggy's voice, Grey DeLisle does Daphne's voice, and Mindy Cohn does Velma's voice. In each episode, Scooby and the gang go somewhere and encounter a mystery. The mysteries always have a monster or a ghost as the villain; next the gang splits up and finds clues. At the end, Fred sets a trap. After the monster is caught it turns out to be a person in a costume. The villains always have a motive; some might be smugglers, some might be revenge-seekers, they could be anything.
The gang takes a trip, but the No-Faced Zombie has made his way onto the airplane and is trying to get Scooby's face! Now there is an epic chase through airplanes and locations with Scooby and the gang!
The Shadow Creature returns to strike Coolsville with his death-ray that will shoot a laser big enough to destroy Coolsville. But, the gang suspects the weapon is all a hoax when he demands money in exchange for him not using it.