The Scooby Doo Mystery Inc. Reboot is a series spin - off and a sequel to the Scooby Doo Mystery Inc. series.
Scooby Doo - Scooby is a talking dane and the best friend of Shaggy.
Shaggy Rogers - A young teenager who has to be the bait of every traps.
Velma Dinkley - She is a genius.
Fred Jones Jr. - The leader of Mystery Inc.
Daphne Blake - A fasionable mystery - solver teenager girl.
Scrappy Doo - He is the nephew of Scooby and a former antagonist who has returned to destroy the world.
Sheriff Bronson Stone - The sheriif of Crystal Cove.
Fred Jones Sr. - The fake father of Fred.
Mayor Janet Nettles - The current mayor of Crystal Cove.
Hot Dog Water - Velmas best friend and the one who helps the gang other than anyone.
Alice May - A secondary antagonist who is under orders of Mr. E.
Mr. E - His real name is Ricky Owens who sent clues to the gang everytime.
Angel Dynamite - Her real name is Cassidy Williams whose home is a popular hangout of the gang.
Brad & Judy - They are the real parents of Fred.
Prof. Pericles - A semi - antagonist talking parrot.
Fruitmeir - A man whom Shaggy asks for food everyday.
Hex Girls - The Hex Girls are a band in Crystal Cove.